Start where your patients are.
Scale when you’re ready.
Every device runs the same MA-operated Smart-ABI Process and feeds the same EMR-ready, audit-defensible report. Hyperion coaches practices to install one device, perfect the workflow, then expand.

Smart-LEDA+
The only platform combining true cuff-based ABI, TBI, and sudomotor function testing: a complete lower-extremity disease assessment in one workflow, and a strong indicator for painful diabetic neuropathy.
Explore Smart-LEDA+ →
Smart-ABI & Smart-ABI+
True cuff-based ABI with VPR waveforms in about five minutes. Smart-ABI+ adds Toe-Brachial Index for patients with incompressible ankle vessels, common in long-standing diabetes, CKD, and advanced age.
Explore Smart-ABI & ABI+ →
Smart-Neuro
A non-invasive autonomic testing solution that supports evaluation of Cardiac Autonomic Neuropathy (CAN) and Peripheral Autonomic Neuropathy (PAN), designed for CPT 95921 and 95923.
Explore Smart-Neuro →Compare the Smart-ABI family
Every device feeds the same Smart-ABI Hub report. The rows below show what each one tests, which CPT codes its studies are designed for, and the practices it fits.
| Smart-ABI | Smart-ABI+ | Smart-LEDA+ | Smart-Neuro | |
|---|---|---|---|---|
| What it tests | True cuff-based, four-limb ABI with VPR waveforms | ABI with VPR, plus Toe-Brachial Index (TBI) | ABI with VPR, TBI, sudomotor function, microvascular data | Cardiac Autonomic Assessment and Sudomotor Function Analysis (HRV, parasympathetic and sympathetic reflex tests, sweat response) |
| Designed for CPT | 93922, 93923 | 93922, 93923 | 93922, 93923 (vascular); 95923 (sudomotor) | 95921, 95923 |
| Study time | About 5 minutes | About 5 minutes; TBI adds about 2 minutes | About 5 minutes vascular, about 7 minutes with sudomotor | |
| Who runs it | Medical assistant | Medical assistant | Medical assistant | Practice staff; no specialized technician required |
| Best fit | Wound care, cardiology and vascular, primary care and NP-led practices | Podiatry and foot-and-ankle; patients with incompressible ankle vessels (diabetes, CKD, advanced age) | Endocrinology and diabetic care, nurse practitioners, wound care, ACOs and value-based care | General neurology, autonomic disorders clinics, peripheral and diabetic neuropathy workups |
| Smart-ABI Hub reports | Yes | Yes | Yes | Yes |
Payment for a service a code describes is not guaranteed and depends on documentation and medical necessity. Reimbursement and ROI →
Descriptors: AMA CPT, as quoted by AAPC (93922, 93923) and Aetna Clinical Policy Bulletin 0485 (95921, 95923), accessed October 31, 2026. Test content, study times, operator and CPT design claims: Hyperion Medical product materials.

Smart-ABI Hub
The recurring layer behind every device: color-coded ABI/VPR reports with patient trending, packaged for major EMRs, with a secure read-out workflow that routes signed reports between front-line providers and qualified specialists, designed to satisfy CMS/RAC documentation requirements.
One report. Read, signed, and in the EMR.
The report brings together Ankle-Brachial Index, Volume Plethysmography Records (VPR) waveforms, patient trending, and additional medical markers in a simple, color-coded format.
- Easy to access, simple to review: read, signed, and added to most major EMRs.
- Specialist read-out workflow: route reports to qualified specialists for interpretation and signature.
- HIPAA-secure, HITRUST-certified: stored locally and on certified cloud servers.
For over a decade, the American Heart Association has recommended that every at-risk patient have an Ankle-Brachial Index performed to assess the probability of peripheral artery disease.
Smart-ABI brings that recommendation into your exam room: at the point of care, in five minutes, with documentation built for the way claims are reviewed today.
See the test in your own workflow.
Book a demo and a Smart-ABI specialist will walk your team through patient selection, the MA-operated workflow, reimbursement, and the report your EMR receives.

