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Autonomic testing for modern neurology

Bring autonomic insight into routine care.

Smart-Neuro is a non-invasive autonomic testing solution designed to help support the evaluation of Cardiac Autonomic Neuropathy (CAN) and Peripheral Autonomic Neuropathy (PAN), with a fast workflow, simple setup, and clear, interpretable reports.

Non-invasiveObjective & quantitativeDesigned for CPT 95921 and 95923
Schedule a Demo →How it works
Smart-Neuro device tray holding a blood pressure cuff, pressure gauge, pulse oximeter, and two electrode pads
The Smart-Neuro device: blood pressure cuff, pressure gauge, pulse oximeter, and electrode pads.
Why Smart-Neuro

Objective answers where the exam is usually qualitative.

Autonomic involvement is easy to suspect and hard to quantify. Smart-Neuro delivers objective autonomic function assessment that helps you identify involvement earlier and support more informed clinical decisions.

  • Objective autonomic function assessment instead of a qualitative chart note.
  • Fast workflow with simple setup that fits into a routine visit.
  • Non-invasive, patient-friendly testing.
  • Clear, interpretable reports that streamline integration into clinical workflow.

What Smart-Neuro delivers

  • Cardiac Autonomic Assessment report: HRV markers and cardiac autonomic reflex tests.
  • Sudomotor Function Analysis report: Sweat Peak and Nitric Oxide Peak by foot.
  • Designed for CPT 95921 and 95923 documentation.
  • Signed, color-coded reports in the Smart-ABI Hub, ready to add to your EMR.
  • On-site installation and staff training on the five-step workflow.
How Smart-Neuro works

Five guided steps, real-time capture.

A simple, repeatable sequence: no specialized technician required.

1

Prepare

Position the patient and review the protocol.

2

Connect

Connect the blood pressure cuff and pulse oximeter.

3

Measure

Capture autonomic responses in real time.

4

Analyze

Advanced algorithms interpret and quantify results.

5

Report

Generate clear, comprehensive reports.

Inside the report

A complete autonomic picture.

Smart-Neuro produces a Cardiac Autonomic Assessment and a Sudomotor Function Analysis, quantifying both branches of the autonomic nervous system.

HRV analysis baselineHeart-rate variability markers (Total Power, SDANN) estimating overall autonomic homeostatic response.
Parasympathetic reflex testsValsalva ratio, E/I ratio, and K30/15 ratio (cardiac autonomic reflex tests, including POTS risk).
Sympathetic reflex testsDelta systolic and diastolic pressure response to standing (orthostatic hypotension / intolerance).
Sudomotor function analysisSweat Peak and Nitric Oxide (NO) Peak by foot, estimating sweat response and microcirculatory response.
Cardiac Autonomic Assessment Sample report
Smart-Neuro sample Cardiac Autonomic Assessment: HRV analysis baseline, parasympathetic tests (Valsalva ratio, E/I ratio, K30/15 ratio) and sympathetic tests, each with a result and reference range.

Markers table from a Smart-Neuro sample report. Patient details removed. Select the image to view it full size.

Sudomotor Function Analysis Sample report
Smart-Neuro sample Sudomotor Function Analysis: Sweat Peak and Nitric Oxide (NO) Peak results for the left and right foot with reference ranges in millivolts.

Results table from a Smart-Neuro sample report. Patient details removed. Select the image to view it full size.

Report markers per the Smart-Neuro OXI_W (Cardiac Autonomic Assessment) and SWEATC (Sudomotor Function Analysis) sample reports. All results should be considered within the clinical context of the patient; interpretation of the results is the responsibility of the medical doctor.

Clinical applications

When to consider testing.

Built for general neurology, autonomic disorders clinics, peripheral and diabetic neuropathy workups, and longitudinal monitoring.

Orthostatic & syncope symptoms

Orthostatic intolerance, dizziness, or unexplained syncope.

Suspected dysautonomia

Suspected dysautonomia or small-fiber neuropathy.

Diabetic autonomic symptoms

Diabetic patients with autonomic symptoms.

Sweating & vasomotor complaints

Abnormal sweating, GI, bladder, or vasomotor complaints.

Monitoring over time

Monitoring disease progression and treatment response.

After you order

We install, we train, we stay.

What happens between the order and your first patient test.

1

On-site installation

A Smart-ABI representative installs Smart-Neuro in your practice and integrates it into your workflow, rather than shipping a box.

2

Staff training

Your staff are trained on the five-step Smart-Neuro workflow and the report, so testing runs without a specialized technician.

3

Smart-ABI Hub setup

Hub access is set up so signed, color-coded reports are ready to add to your EMR.

4

Ongoing support

Technical support and customer service continue after installation. The Extended Service Agreement adds Hub access, unlimited support, and the extended software warranty.

Questions

Smart-Neuro FAQ

What is Smart-Neuro?
A non-invasive autonomic testing solution designed to help support the evaluation of Cardiac Autonomic Neuropathy (CAN) and Peripheral Autonomic Neuropathy (PAN).
How does it work?
The clinician positions the patient and reviews the protocol, connects a blood pressure cuff and pulse oximeter, captures autonomic responses in real time, and advanced algorithms interpret and quantify the results into a clear, comprehensive report.
Which CPT codes does Smart-Neuro support?
Smart-Neuro is designed for CPT 95921 and 95923 compliance. As always, payment for a service a code describes is not guaranteed and depends on documentation and medical necessity.
When should autonomic testing be considered?
For orthostatic intolerance, dizziness, or unexplained syncope; suspected dysautonomia or small-fiber neuropathy; diabetic patients with autonomic symptoms; abnormal sweating, GI, bladder, or vasomotor complaints; and to monitor progression and treatment response.
Which practices is Smart-Neuro built for?
General neurology, autonomic disorders clinics, peripheral neuropathy evaluation, diabetic neuropathy workups, and follow-up and longitudinal monitoring.

Empower your neurology practice with autonomic insight.

Book a free demonstration and a Smart-Neuro specialist will walk your team through the setup, the five-step workflow, the report, and CPT 95921 and 95923 documentation.

Schedule a Demo → Call (877) 275-8760
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